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Home/Powders/ReadyBlend Sustained-Release
Direct-Compression · HPMC Matrix Blend

ReadyBlend Sustained-Release
Tableting Powder

A sustained-release tableting powder built on an HPMC matrix — the active ingredient diffuses out through a swelling gel layer instead of releasing all at once. Built for once- or twice-daily dosing formats.

Request Bulk Pricing Compare to Standard ReadyBlend
8–12 hr
Target Release Window
15–40%
Typical Mix Ratio
White
Uncolored, as shipped
2 yrs
Shelf Life
$89.00 USD / bag

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ReadyBlend® Sustained-Release FIG. 01 ReadyBlend Sustained-Release direct-compression powder, Press & Powder branded 1kg bag
Why This Blend

Built to
slow release.

01

HPMC Matrix Former

Hydroxypropyl methylcellulose swells into a gel layer on contact with fluid, controlling how fast the active can diffuse out rather than releasing it all at once.

02

Pre-Balanced, Not From Scratch

Matrix ratio is pre-balanced against filler and lubricant, so you're not separately sourcing and titrating polymer grade and loading.

03

Same Press, Same Process

Directly compressible on the same TDP-pattern equipment as standard ReadyBlend — no granulation or coating step required.

Full Specifications

Every
number.

Release profile depends on tablet hardness and your active ingredient — confirm with your own dissolution testing before a production run.

SpecValue
AppearanceWhite powder
Key ingredientsHydroxypropyl methylcellulose (HPMC), microcrystalline cellulose, dicalcium phosphate, magnesium stearate
Physical stateSolid
Directly compressibleYes
Typical mix ratio15–40% of total tablet weight
Target release window8–12 hours (formulation-dependent)
Approx. mesh size100–200 mesh
StorageRoom temperature, 10–30°C once opened, sealed container
Shelf life2 years from batch date, unopened
Bag sizes1 kg, 5 kg, 10 kg, 50 kg
Bulk sizes500 kg, 1 ton, 2 ton, 5 ton pallet lots
Questions

Frequently
asked.

How does it control release speed?

It uses hydroxypropyl methylcellulose (HPMC), a swellable polymer, as a matrix former. As the tablet contacts fluid, the HPMC swells into a gel layer that slows how quickly the active ingredient can diffuse out.

What release profile does it target?

It's designed as a starting point for 8–12 hour extended-release formulations. Actual release profile depends on tablet hardness, HPMC grade, and your active ingredient — confirm with your own dissolution testing.

Is the mix ratio the same as standard ReadyBlend?

No — the HPMC matrix takes up more volume than a standard filler system, so typical active loading is lower, usually 15–40% rather than standard ReadyBlend's 20–60%.

Does it need different equipment?

No — it's directly compressible on the same TDP-pattern presses, though matrix tablets often benefit from a slightly deeper fill depth and firmer compression.

Reviews

What buyers
say.

4.7 out of 5, based on 3 reviews.

★★★★★
Naomi C. April 2026

Steady release profile in our dissolution testing — matched what we needed for once-daily dosing.

★★★★★
Eric J. February 2026

Straightforward to formulate with, and the HPMC matrix behaved consistently across batches.

★★★★☆
Sana R. December 2025

Good product, though sustained-release testing took longer to dial in than we expected — worth the effort.

Also Consider

Round out
the line.

POWDER

Standard ReadyBlend

The all-in-one blend for most actives, in nine food-grade colors.

View product → POWDER

ReadyBlend Fast-Disintegrating

A superdisintegrant blend for quick-dissolve tablet formats.

View product → MODEL TDP-5

TDP-5

Enough force for firmer matrix tablets once a formulation is dialed in.

View product →

Questions about Sustained-Release ReadyBlend?

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